Silanyl phenols and naphthols

Organic compounds -- part of the class 532-570 series – Organic compounds – Silicon containing

Reexamination Certificate

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C556S465000

Reexamination Certificate

active

07078550

ABSTRACT:
There are described silanyl phenols and naphthols of formula (1a) or (1b), wherein R1is hydrogen; halogen; hydroxy; C1–C20alkyl; C3–C12cycloalkyl; C1–C20alkoxy; trifluoromethyl; pentafluoroethyl; mono- or di-C1–C5alkylamino; hydroxy-C1–C5alkyl; or phenyl, phenyl-C1–C20alkyl, phenoxy, phenyl-C1–C20alkoxy, naphthyl or naphthyl-C1–C20alkyl each unsubstituted or substituted by C1–C5alkyl, C3–C12cycloalkyl, C1–C5alkoxy, C3–C12cycloalkoxy, halogen, oxo, carboxy, carboxy-C1–C7alkyl ester, carboxy-C3–C12cycloalkyl ester, cyano, trifluoromethyl, pentafluoroethyl, amino, N,N-mono- or di-C1–C20alkylamino or by nitro; R2, R3and R4are each independently of the others hydrogen; C1–C20alkyl; or C3–C12-cycloalkyl; R5, R6and R7are each independently of the others C1–C20alkyl, C5–C10aryl, C1–C20alkoxy, phenyl-C1–C20alkyl, phenyl-C1–C20alkoxy, C2–C5alkenyl, —O—Si—(C1–C5alkyl)3; or O—Si—(C1–C5alkyl)2-O—Si(C1–C5alkyl)3and n is 0 or 1. The compounds exhibit a pronounced activity against Gram positive and Gram negative bacteria, and also against yeasts and moulds

REFERENCES:
patent: 3705075 (1972-12-01), Marzocchi
patent: 5063134 (1991-11-01), Horiguchi et al.
patent: 5756485 (1998-05-01), Richard et al.
patent: 1812951 (1969-07-01), None
patent: 3810247 (1988-10-01), None
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John McMurry, Organic Chemistry Textbook, 3rdEdition, p. 1023, 1992.
Chemical Abstracts vol. 124, No. 2, No. 10139 (1996) for JP 07196804.
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Bruce et al., J. Chem. Soc., Perkin Trans. 1 (1981), (10), pp. 2677-2679.
English abstract for EP 0412407 (1991).
Derwent Abstract 1967-06212H for DE 1812951 (1969).

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