Chemistry: analytical and immunological testing – Optical result – With fluorescence or luminescence
Reexamination Certificate
2008-06-24
2008-06-24
Helms, Larry R. (Department: 1641)
Chemistry: analytical and immunological testing
Optical result
With fluorescence or luminescence
C436S546000, C436S904000, C435S028000, C568S001000, C549S213000
Reexamination Certificate
active
07390670
ABSTRACT:
Methods and compound useful for detecting a source of hydrogen peroxide are disclosed wherein a signalling compound of the formula:is reacted with peroxide. Sig is a non-polymeric organic group, B is a boron atom, and each R is independently selected from hydrogen, alkyl and aryl groups and can be joined together as a straight or branched alkylene chain forming a ring or as an aromatic ring. A detectable product compound of the formula Sig—OH or Sig—O−is produced and detected by measuring color, absorbance, fluorescence, chemiluminescence, or bioluminescence. The signalling compound itself does not possess the detectable property or does so only to a very weak degree. The methods can be used as a detectable signal in assays for peroxide or peroxide-producing enzymes and in assays employing enzyme-labeled specific binding pairs.
REFERENCES:
patent: 4496722 (1985-01-01), Gallop et al.
patent: 4659817 (1987-04-01), Gallop
patent: 5183653 (1993-02-01), Linder et al.
patent: 5242842 (1993-09-01), Sundrehagen
patent: 5506144 (1996-04-01), Sundrehagen
patent: 5512451 (1996-04-01), Kricka
patent: 5613364 (1997-03-01), Higgins
patent: 5629168 (1997-05-01), Kricka
patent: 5723295 (1998-03-01), Akhavan-Tafti et al.
patent: 5739318 (1998-04-01), Frantzen
patent: 5922558 (1999-07-01), Akhavan-Tafti
patent: 6873914 (2005-03-01), Winfield et al.
patent: 02/46752 (2002-06-01), None
Akhavan-Tafti Hashem
Eickholt Robert A.
Handley Richard S.
Lauwers Kenneth S.
Handley Richard S.
Haq Shafiqul
Helms Larry R.
Lumigen Inc.
LandOfFree
Signalling compounds and methods for detecting hydrogen... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Signalling compounds and methods for detecting hydrogen..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Signalling compounds and methods for detecting hydrogen... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2812597