Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Reexamination Certificate
2004-12-06
2009-10-06
Mondesi, Robert B (Department: 1645)
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
C424S184100, C530S300000, C435S069700, C536S023700
Reexamination Certificate
active
07597895
ABSTRACT:
Compounds that competitively inhibit binding of CSP toS. mutanshistidine kinase are provided. The compounds are preferably a peptide or an antibody, and are preferably a derivative of [SEQ ID NO:2], a fragment of [SEQ ID NO:2] or a derivative of a fragment of [SEQ ID NO:2]. Methods of making these compounds and their use for inhibiting the growth ofS. mutans, for inhibiting dental caries, and for improving dental health are also disclosed.
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Cvitkovitch Dennis G.
Huang Yi-Chen Cathy
Levesque Celine
Baskar Padma V
Dorn Brian R.
Merchant & Gould P.C.
Mondesi Robert B
The Governing Council of the University of Toronto
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