Signal peptides, nucleic acid molecules and methods for...

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

Reexamination Certificate

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C424S184100, C530S300000, C435S069700, C536S023700

Reexamination Certificate

active

07597895

ABSTRACT:
Compounds that competitively inhibit binding of CSP toS. mutanshistidine kinase are provided. The compounds are preferably a peptide or an antibody, and are preferably a derivative of [SEQ ID NO:2], a fragment of [SEQ ID NO:2] or a derivative of a fragment of [SEQ ID NO:2]. Methods of making these compounds and their use for inhibiting the growth ofS. mutans, for inhibiting dental caries, and for improving dental health are also disclosed.

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