Signal noise reduction for imaging in biological analysis

Optics: measuring and testing – By dispersed light spectroscopy – With background radiation comparison

Reexamination Certificate

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C356S318000, C356S417000, C250S458100

Reexamination Certificate

active

10913601

ABSTRACT:
A system and method for characterizing contributions to signal noise associated with charge-coupled devices adapted for use in biological analysis. Dark current contribution, readout offset contribution, photo response non-uniformity, and spurious charge contribution can be determined by the methods of the present teachings and used for signal correction by systems of the present teachings.

REFERENCES:
patent: 6518068 (2003-02-01), Gambini et al.
patent: WO 01/07896 (2001-02-01), None
“Getting the Right CCD,” Photonics Tech Briefs, Sep. 1999.
William Des Jardin and Stephen Kosman, “True Two-Phase CCD Image Sensors Employing a Transparent Gate,” Presented at Photonics West, Jan. 1999.
“Interlace Operation in TI Virtual-Phase CCD Image Sensors,” Texas Instruments, Jan. 1993.
International Search Report and the Written Opinion of the International Searching Authority for Application No. PCT/US2005/028066 mailing date Mar. 2, 2006.

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