Side-wall heater for thermocycler device

Details Side-wall heater for thermocycler device Side-wall heater for thermocycler device

2002-10-01

2008-12-02

Beisner, William H. (Department: 1744)

Chemistry: molecular biology and microbiology

Apparatus

Including condition or time responsive control means

C435S303100, C435S809000, C435S091200, C435S288700, C422S091000, C422S105000, C165S206000

Reexamination Certificate

active

07459302

ABSTRACT:
The invention relates to an apparatus and methods for preventing condensation on the interior surfaces of sample tubes which are being exposed to temperature cycles, such as during a PCR amplification reaction. In particular, the invention relates to apparatus comprising a sample block comprising a plurality of sample wells for receiving sample tubes and heating elements disposed in the sample wells for heating at least a portion of the sides of sample tubes (e.g., at least the portion which forms the head space after a tube is filled with a PCR reaction mixture). In a preferred aspect, the sample block is part of a thermocycling device for performing PCR and the side-wall heater is used to enhance uniformity and speed of amplification reactions. For example, by decreasing or eliminating condensation, signal strength jumps in a real-time PCR assay can be minimized as can reaction non-homogeneity.

REFERENCES:
patent: 5645801 (1997-07-01), Bouma et al.
patent: 5670120 (1997-09-01), Degenhardt et al.
patent: 6153426 (2000-11-01), Heimberg
patent: 6638761 (2003-10-01), Shin et al.
patent: 3441179 (1986-05-01), None
patent: 42 17 868 (1993-12-01), None
patent: 0 488 769 (1992-06-01), None
patent: WO 89/10789 (1989-11-01), None
International Search Report of International Application No. PCT/US02/31143, Feb. 14, 2003.

Affiliated with

Also associated with

Rating

Side-wall heater for thermocycler device does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Side-wall heater for thermocycler device, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Side-wall heater for thermocycler device will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4034916