Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – 9,10-seco- cyclopentanohydrophenanthrene ring system doai
Patent
1985-11-04
1988-01-12
Schenkman, Leonard
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
9,10-seco- cyclopentanohydrophenanthrene ring system doai
2603972, A61K 3159, C07J 900
Patent
active
047192054
ABSTRACT:
Novel 1-hydroxylated vitamin D compounds containing a 22, 23-cis double bond in the side chain are provided. The compounds are characterized by an unexpectedly high binding affinity for the protein receptor forecasting their ready applicability as substitutes for vitamin D or various of its metabolites in their various known applications and in the treatment of various metabolic bone diseases.
REFERENCES:
patent: 3907843 (1975-09-01), DeLuca et al.
patent: 4225596 (1980-09-01), DeLuca
patent: 4610978 (1986-09-01), Dikstein et al.
DeLuca Hector F.
Schnoes Heinrich K.
Sicinski Rafal R.
Tanaka Yoko
Bremer Howard W.
Lipovsky Joseph A.
Schenkman Leonard
Wisconsin Alumini Research Foundation
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