Side chain chlorination process of heterocycles

Details Side chain chlorination process of heterocycles Side chain chlorination process of heterocycles

1986-04-18

1988-01-12

Berch, Mark L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

260694, 544216, 544224, 544242, 544336, 544353, 546101, 546139, 546180, 546346, C07B 3900, C07D24142, C07D21326, C07D21512

Patent

active

047192984

ABSTRACT:
A novel method of chlorinating the alkyl side chains of a nitrogen containing heterocyclic comprising reacting an alkyl substituted heterocycle with trichloroisocyanuric acid at temperatures of 20.degree. to 200.degree. C. to obtain the same in high yields.

REFERENCES:
Ziegler et al., Ann. 551, 80 (1942).
Juenge et al., J. Org. Chem. 35, 719 (1970).
Mura et al., Tet. Lett. 50, 4433 (1975).

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