Side-chain alkylation method

Chemistry of hydrocarbon compounds – Aromatic compound synthesis – By condensation of entire molecules or entire hydrocarbyl...

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585446, 585452, C07C 266

Patent

active

054141745

ABSTRACT:
There is disclosed a side-chain alkylation reaction wherein an alkyl aromatic compound having a benzyl hydrogen is reacted with unsaturated hydrocarbons to produce a desired target product with excellent selectivity. The reaction is conducted in the presence of an alkyl ether and an alkaline metal catalyst. In comparison with conventional methods, it was observed that target selectivity was improved remarkably when equimolar addition of the reactants was employed, that very little catalyst was needed, and that the catalyst could be treated as a linear or uniform system, allowing the reaction to be easily scaled to meet industrial requirements.

REFERENCES:
patent: 2993050 (1961-07-01), Gleason et al.
patent: 3244758 (1966-04-01), Eberhardt
patent: 3468970 (1969-09-01), Screttas
patent: 3651161 (1972-03-01), Waragai et al.
patent: 3742077 (1973-06-01), Kamienski et al.
patent: 5030784 (1991-07-01), Slaugh

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