Sialosylceramides and production method thereof

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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549416, 549417, 549419, C07D30900, C07D30902

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active

047300582

ABSTRACT:
This invention provides a novel compound expressed by the following formula (1): ##STR1## [wherein R.sup.1 denotes a hydrogen atom or CH.sub.3 CO--, R.sup.2 denotes --COOR.sup.4 (R.sup.4 denotes Na or a methyl group) or ##STR2## (R.sup.5 denotes a hydrogen atom, --COC.sub.6 H.sub.5 or --Si(C.sub.6 H.sub.5).sub.2 C(CH.sub.3).sub.3 and R.sup.3 denotes ##STR3## (R.sup.5 denotes a hydrogen atom, --COC.sub.6 H.sub.5 or --Si(C.sub.6 H.sub.5).sub.2 C(CH.sub.3).sub.3) when R.sup.2 is --COOR.sup.4 (R.sup.4 denotes Na or a methyl group) or denotes --COOR.sup.4 when R.sup.2 is ##STR4## and a method of preparation thereof. The above novel compounds of present invention are useful as a tumor maker, a molecular marker for cells having the ability of differential induction, or an intermediate of the synthesis thereof. 'Y

REFERENCES:
patent: 3939043 (1976-02-01), Nara et al.
patent: 4120824 (1978-10-01), Crutchfield et al.
Carbohydrate Research, vol. 128, 1984, pp. C1-C4, Elsevier Science Publishers B.V., Amsterdam, NL; T. Ogawa et al: "Synthesis of Alpha- and Beta-(2-9)-Linked Disialyglycerolipids", European Search Report 87 10 5321.

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