Sialidase and recombinant cell lines

Details Sialidase and recombinant cell lines Sialidase and recombinant cell lines

2005-07-12

2005-07-12

Ketter, James (Department: 1636)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C536S023500, C435S200000

Reexamination Certificate

active

06916916

ABSTRACT:
A recombinant cell line has a constitutive sialidase whose functional expression is disrupted, for example by homologous recombination or using antisense RNA. Sialidase is purified from cell culture fluid of Chinese hamster ovary cells. Nucleic acid encoding sialidase is obtained using an oligonucleotide probe designed using amino acid sequence data on the sialidase.

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