Sialic acid powder and process for the preparation thereof

Details Sialic acid powder and process for the preparation thereof Sialic acid powder and process for the preparation thereof

1994-12-16

1997-10-21

Kight, John

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

536 172, 536 185, 536124, 536127, A61K 3170, C07H 100

Patent

active

056796455

ABSTRACT:
An amorphous sialic acid powder is disclosed. It is prepared by rapidly freezing an aqueous solution of sialic acids and freeze-drying the frozen product. It has a melting point of 131.degree.-136.degree. C. (decomposed) and exhibits no peaks inherent to crystals in differential scanning thermal analysis (at 165.degree.-200.degree. C.) and X-ray diffractiometric pattern (in the range of 5.degree..ltoreq.2.theta..ltoreq.40.degree.). The amorphous sialic acid powder is highly reactive and can be used as a raw material for drugs and the like.

REFERENCES:
patent: 4002748 (1977-01-01), Bornstein et al.
patent: 4042576 (1977-08-01), Eustache
patent: 4526727 (1985-07-01), Petty
patent: 5118516 (1992-06-01), Shimatani et al.

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