Sialic acid derivative and process for preparing the same

Details Sialic acid derivative and process for preparing the same Sialic acid derivative and process for preparing the same

1985-03-06

1987-09-01

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 24, 536 553, C07H 1700

Patent

active

046910123

ABSTRACT:
A novel N-acetylneuraminic acid derivative, represented by the general formula: ##STR1## wherein the R.sup.1 groups are, independently, hydrogen or acetyl; R.sup.2 is a nucleoside residue; and R.sup.3 is carboxyl or methoxycarbonyl.
The N-acetylneuraminic acid derivative is useful in inhibiting metastasis of cancer cells. Also provided is a process for the preparation of the derivatives.

REFERENCES:
patent: 3501456 (1970-03-01), Shen et al.
patent: 4447600 (1984-05-01), Ogura et al.

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