SET1 proteins and uses thereof

Details SET1 proteins and uses thereof SET1 proteins and uses thereof

2004-12-07

2010-11-23

Cheu, Jacob (Department: 1641)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

C435S007200

Reexamination Certificate

active

07838244

ABSTRACT:
The invention relates to methods of use of SET1 proteins or functional equivalents thereof. More particularly the invention relates to the use of SET1 proteins or functional equivalents thereof in procedure, for identification and/or isolation of IgA and the scrum complement factor C5.

REFERENCES:
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patent: WO 02/077183 (2002-10-01), None
patent: WO 02/094868 (2002-11-01), None
patent: WO2005/092918 (2005-10-01), None
Nislow et al. Molecular Biology of the Cell 1997, vol. 8, p. 2421-2436.
Langley, Ries, et al, “The Staphylococcal Superantigen-Like Protein 7 Binds IgA and Complement C5 and Inhibits IgA-FcαRI Binding and Serum Killing of Bacteria.” Journal of Immunology, 2005, 174:2926-2933.
Haas, Pieter-Jan, et al, “The Structure of the C5a Receptor-blocking Domain of Chemotaxs Inhibitory Protein ofStaphylococcus aureusis Related to a Group of Immune Evasive Molecules.”J. Mol. Biol. (2005) 353, 859-872.
Rooijakkers, Suzan H.M., et al, “Staphylococcal Innate Immune Evasion.”,TRENDS in Microbiologyvol. 13 No. 12 Dec. 2005, pp. 596-601.
Kanwar, Jagat R., et al; “β7 Integrins Contribute to Demyelinating Disease of the Central Nervous System”; Journal of Neuroimmunology (103) (2000) 146-152.
Krissansen, Geoffrey W., et al, A Pseudosymmetric Cell Adhesion Regulatory Domain in the β7 Tail of the Integrin α4β7 That Interacts With Focal Adhesion Kinase and SRC, Eur. J. Immunol. 2006. 36:2203-2214.
Yuan et al. “Cloning and sequence analysis of a novel beta 2-related integrin transcript form T lymphocytes: homology of intergrin cysteine-rich repeats to domain III of lamini B chains,” Int Immunol. 1990;2(11):1097-108, Erratum in: Int Immunol. Dec. 1991;3(12);1373-4.
Yuan et al. “Molecular Cloning of the mouse Integrin beta 7 Subunit” J Biol Chem. Apr. 15, 1992;267(11):7352-8.
Arcus et al., “The Three-Dimensional Structure of a Superantigen-like Protein, SET3, from a Pathogenicity Island of theStaphylococcus aureusGenome”, The Journal of Biological chemistry 277:32274-32281, 2002.
Baba et al, “Genome and Virulence Determinants of High Virulence Community-Acquired MRSA”, The Lancet 359:1819-1827, 2002.
Fraser et al., “The Staphylococcal SETs—Superantigen Like Virulence Factors Targeting IgA and Complement Factors.”, Conference Presentation, Australian Society for Immunology 2003, Perth, Western Australia, Abstract submitted Sep. 15, 2003; Conference opened Jul. 12, 2003; oral presentation delivered Oct. 12, 2003. Abstract and PowerPoint™ presentation attached.
Holden et al., “Complete Genomes of Two ClinicalStaphylococcus aureusStrains: Evidence for the Rapid Evolution of Virulence and Drug Resistance”, Proceedings of the National Academy of Sciences (USA) 101:9786-9791, 2004.
Kuroda et al., “Whole Genome Sequencing of Meticillin-ResistantStaphylococcus aureus”, The Lancet 357:1225-1240, 2001.
Langley et al., “The Staphylococcal Superantigen-Like Protein 7 Binds IgA and Complement C5 and Inhibits IgA-FcRI Binding and Serum Killing of Bacteria”, The Journal of Immunology 174:2926-2933, 2005.
Williams et al., “Identification of a Novel Gene Cluster Encoding Staphylococcal Exotoxin-Like Proteins: Characterization of the Prototypic Gene and Its Protein Product, SET1”, Infection and Immunity 68:4407-4415, 2002.
TrEMBLE Accession No. Q8NY48. Set22 protein. Oct. 1, 2002. Baba et al., (94% identical (Blastp) to Applicant's Seq ID 6).

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