Chemistry: analytical and immunological testing – Composition for standardization – calibration – simulation,... – Blood serum or blood plasma standard or control
Patent
1993-04-13
1994-05-03
Alexander, Lyle A.
Chemistry: analytical and immunological testing
Composition for standardization, calibration, simulation,...
Blood serum or blood plasma standard or control
436 17, 436 18, 436817, G01N 3378, G01N 3396
Patent
active
053087682
ABSTRACT:
A blood serum sample useful as a calibration baseline comprising a natural blood matrix is disclosed. This serum sample contains less than an HPLC-detectable amount of cortisol. Also disclosed is a serum sample containing less than HPLC-detectable amounts of cortisone and corticosterone and less than RIA-detectable amounts of testosterone, androstenedione, progesterone, DHEA sulfate and 17-OH progesterone. A method of preparing such a serum sample is also disclosed.
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"Evaluation of SeraSub.TM.. . . For Making Calibrators and Controls for Drugs of Abuse", Clin. Chem. 37(6) 1991, Akerka.
"Evaluation of SeraSub.TM. a substitute . . . for making calibrators and controls", Alan P. Schwartz, Clin Chem 36(6) 1025, Jul. 1990.
Poster presented Jul., 1992 "Determination of cortisol (c), cortisone (cn), corticosterone (cc), prednisone (p), and prednisolone (pl) in serum with solid reversed-phase extraction and high performance liquid chromatography (HPLC)". Gary L. Lensmeyer, et al., Clin. Labs., (Univ. Wisc. Hosp. & Clinics, Dept. Path. & Lab. Med., Madison, Wis.).
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McBride, et al., "Rapid Liquid-Chromatographic Method for Simultaneous Determination of Plasma Prednisone, Prednisolone, and Cortisol in Pediatric Renal-Transplant Recipients", Clinical Chemistry, vol. 37, No. 5:643-646, 1991.
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Advertisement from Biomedical Products, Jul., 1992 "Scantibodies Laboratory, Steroid Free Human Serum in Two Forms".
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Alexander Lyle A.
Bhat N.
Wisconsin Alumni Research Foundation
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