Serum/plasma separators with centrifugal valves

Liquid purification or separation – Flow – fluid pressure or material level – responsive – Discharge of treated material

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Details

210359, 210516, 210DIG23, B01D 2126

Patent

active

039310108

ABSTRACT:
A self-contained fluid separator assembly is disclosed capable of separating blood into its component parts of plasma or serum, the light phase, and the cellular portion, the heavy phase. The assembly comprises a container having at least one open end for receiving blood for subsequent separation and a closure sealing the open end of the container. The closure is formed of a self-sealing elastomeric material which is penetrable by a pointed hollow needle through which the blood to be separated is conducted into the container. A piston is slidably disposed in the container with its outer surfaces in sealing contact with the inner surfaces of the container. Centrifugally actuated valve means is provided on the piston which is normally closed and automatically opens in response to centrifugal force. When blood in the container is subjected to centrifugal force it first separates into its light phase and heavy phase. Thereafter the piston with open valve moves down through the light phase while retaining sealing engagement with the inner surfaces of the container. Positive stop means is provided on the container between its ends so that the piston as it moves through the light phase will contact the stop means and stop at a predetermined distance above the bottom of the tube. Then the valve means automatically closes to provide an impervious barrier between the separated light and heavy phases of the blood.

REFERENCES:
patent: 2577780 (1951-12-01), Lockhart
patent: 3661265 (1972-05-01), Greenspan
patent: 3779383 (1973-12-01), Ayres
patent: 3786985 (1974-01-01), Blaivas
patent: 3814248 (1974-06-01), Lawhead

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