Chemistry: molecular biology and microbiology – Spore forming or isolating process
Patent
1987-07-24
1991-06-18
Weimar, Elizabeth C.
Chemistry: molecular biology and microbiology
Spore forming or isolating process
4352401, 4352402, 4352403, 435 701, C12N 500
Patent
active
050249479
ABSTRACT:
Serum-free media which support the growth of insect cells and the production thereby of recombinant proteins and viral products are herein disclosed. The serum free media can support insect cell growth at large scale under agitated and/or sparged, preferably well-aerated conditions.
The serum free medium disclosed support insect cell growth to cell densities comparable to serum-containing culture and the production of viral and recombinant products to levels equivalent to those found in serum containing culture.
REFERENCES:
patent: 30985 (1982-06-01), Cartaya
patent: 4485029 (1984-11-01), Kato et al.
patent: 4752585 (1988-06-01), Koths et al.
The Merck Index, 9th edition, Merck & Co., Inc. (1976), pp. 7349, 2435.
Smith et al.(b), Proc. Natl. Acad. Sci. 82:8404-8408 (1985).
Brooks et al., in "Verteb. Syst. in Vitro", eds Kinstak et al., Elsevier, Amsterdam, Netherlands (1980), pp. 67-77.
Mitsuhashi, Adv. in Cell Culture 2:133,156-7, 182-3 (1982).
Kawasaki et al., Science, 230:291-296 (1985).
Keay, Methods Cell Biol., 20:169,194-195 (1978).
Miltenburger, in "Horm: Def. Media", eds. Fischer et al., Springer: Berlin, FRG (1983), pp. 31-43.
Jeang et al., J. Virology, 61:708-713 (1987).
Smith et al. (1), Mol. Cell. Biol., 3:2156-2165 (1983).
Mizrahi, J. Clinical Microbiol., 2(1):11-13 (1975).
Ryan, P. A. et al., 1987, Exp. Cell Res., 172:318.
Bettger, W. J., 1981, PNAS(USA), 78:5588-5592.
Iscove, N. N., 1984, Methods for Serum-Free Culture of Neuronal and Lymphoid Cells, 4:169-185.
Mizrahi, A., 1984, Devel. Biol. Standard, 55:93-102.
Derwent Publication (Abstract Only), No. 4,476,618.
Kirk-Othmer Encyclopedia of Chemical Technology (John Wiley & Sons, Inc., N.Y.).
Kilburn, et al., 1968, Biotech & Bioengin., X:801-814.
Yamane, et al., 1981, Proc. Japan Acad., 57B(10):385-389.
Inlow Duane
Maiorella Brian
Cetus Corporation
Chambers Jasemine C.
Lauder Leona L.
Weimar Elizabeth C.
Wong Wean Khing
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