Serum and plasma clarification process

Details Serum and plasma clarification process Serum and plasma clarification process

1979-06-04

1981-04-28

Turk, Arnold

Compositions

Nonreactive analytical, testing, or indicating compositions

23230B, 23909, 260112B, G01N 3348, G01N 3392

Patent

active

042644712

ABSTRACT:
A process for obtaining delipified human serum or plasma of low turbidity, and therefore decreased light scattering, is provided. This process comprises the simultaneous steps of deionization and pH adjustment of the serum or plasma to near the isoelectric point of lipoproteins commonly found in sera and results in the precipitation of much of the lipoprotein fraction. The process is carried out utilizing a mixed anion-cation exchange resin. The sera so obtained can be used as base material or a special diluent for verifying analytical information obtained in clinical analyses.

REFERENCES:
patent: 3682835 (1972-08-01), Louderback
patent: 4039285 (1977-08-01), Teipel
patent: 4096136 (1978-06-01), Ayers et al.
patent: 4185963 (1980-01-01), Heuck

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