Serum albumin production

Details Serum albumin production Serum albumin production

1976-09-20

1978-02-21

Schain, Howard E.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260112B, 424101, 424177, C07G 700

Patent

active

040751970

ABSTRACT:
A serum albumin fraction is prepared in high yield and purity from plasma and other albumin-containing blood protein fractions by contacting with a resinous polymeric material having a high capacity for adsorption of albumin, heating at 65.degree.-72.degree. C for about 1-4 hours while maintaining a pH of 5.0-5.5, and then selectively eluting the albumin from the resin-protein mixture at a pH of 3.5-4.5. The resinous polymeric materials are diloweralkylaminoloweralkyl-substituted cross-linked dextran polymers.

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patent: 3992367 (1976-11-01), Plan et al.
Experientia, vol. 30, No. 6, pp. 608-610, 1974, Podhradska et al.
Blut. Band 30, pp. 121-134, 1975, Schneider et al.

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