Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor
Reexamination Certificate
2006-08-01
2006-08-01
Marx, Irene (Department: 1651)
Chemistry: molecular biology and microbiology
Micro-organism, per se ; compositions thereof; proces of...
Bacteria or actinomycetales; media therefor
C435S118000
Reexamination Certificate
active
07083969
ABSTRACT:
There are disclosed a novel microorganismSerratia marcescensstrain and a prodigiosin isolated from the microorganism. The prodigiosin is useful as an immunosuppressive in various fields, including the treatment of the diseases requiring immunosuppression and the basic research for the diseases, the transplantation of the organs or tissues, and the immune cells.
REFERENCES:
patent: 4266028 (1981-05-01), Nakamura et al.
Domingo Gargallo-Viola, Enzyme Polymorphism, Prodigiosin Production, and Plasmid Fingerprints in Clinical and Naturally Occurring Isolates ofSerratia marcescens, Journal of Clinical Microbiology, May 1989, pp. 860-868.
N.R. Thomson, et al., Biosynthesis of carbapenem antibiotic and prodigiosin pigment inSerratiais under quorum sensing control, Molecular Microbiology (2000) 36(3), pp. 539-556.
Sang Bae Han, et al., T-cell specific immunosuppression by prodigiosin isolated fromSerratia marcescens, International Journal of Immunopharmacology 20 (1998), pp. 1-13.
Han Sangbae
Kim Hwanmook
Kim Young-kook
Yoo Sungrak
Korea Research Institute of Bioscience and Biotechnology
Marx Irene
Mathews, Sheperd, McKay & Bruneau, P.A.
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