Serpin enzyme complex receptor--mediated gene transfer

Details Serpin enzyme complex receptor--mediated gene transfer Serpin enzyme complex receptor--mediated gene transfer

1996-06-03

1999-10-26

Campell, Bruce R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

424 9321, 435 78, 435 914, 4353201, 435325, 435455, 53038822, 5308873, 530324, 536 231, A01N 4304

Patent

active

059729015

ABSTRACT:
Nucleic acids are compacted, substantially without aggregation, to facilitate their uptake by target cells of an organism to which the compacted material is administered. The nucleic acids may achieve a clinical effect as a result of gene expression, hybridization to endogenous nucleic acids whose expression is undesired, or site-specific integration so that a target gene is replaced, modified or deleted. The targeting may be enhanced by means of a target cell-binding moiety. The nucleic acid is preferably compacted to a condensed state.

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