Chemistry: molecular biology and microbiology – Vector – per se
Reexamination Certificate
2005-07-05
2005-07-05
Priebe, Scott D. (Department: 1635)
Chemistry: molecular biology and microbiology
Vector, per se
C435S455000, C435S456000, C435S463000, C435S465000, C435S091400, C424S093200
Reexamination Certificate
active
06913922
ABSTRACT:
Adenovirus serotypes differ in their natural tropism. The adenovirus serotypes 2, 4, 5, and 7 all have a natural affiliation towards lung epithelia and other respiratory tissues. In contrast, serotypes 40 and 41 have a natural affiliation towards the gastrointestinal tract. The serotypes described, differ in at least capsid proteins (penton-base, hexon), proteins responsible for cell binding (fiber protein), and proteins involved in adenovirus replication. This difference in tropism and capsid protein among serotypes has led to the many research efforts aimed at redirecting the adenovirus tropism by modification of the capsid proteins.
REFERENCES:
patent: 4487829 (1984-12-01), Sharp et al.
patent: 4517686 (1985-05-01), Ruoslahti et al.
patent: 4578079 (1986-03-01), Ruoslahti et al.
patent: 4589881 (1986-05-01), Pierschbacher et al.
patent: 4593002 (1986-06-01), Dulbecco
patent: 4792525 (1988-12-01), Ruoslahti et al.
patent: 4797368 (1989-01-01), Carter et al.
patent: 4956281 (1990-09-01), Wallner et al.
patent: 5024939 (1991-06-01), Gorman
patent: 5096815 (1992-03-01), Ladner et al.
patent: 5166320 (1992-11-01), Wu et al.
patent: 5198346 (1993-03-01), Ladner et al.
patent: 5204445 (1993-04-01), Plow et al.
patent: 5223394 (1993-06-01), Wallner
patent: 5223409 (1993-06-01), Ladner et al.
patent: 5240846 (1993-08-01), Collins et al.
patent: 5246921 (1993-09-01), Reddy et al.
patent: 5332567 (1994-07-01), Goldenberg
patent: 5349053 (1994-09-01), Landolfi
patent: 5403484 (1995-04-01), Ladner et al.
patent: 5436146 (1995-07-01), Shenk et al.
patent: 5443953 (1995-08-01), Hansen et al.
patent: 5474935 (1995-12-01), Chatterjee et al.
patent: 5521291 (1996-05-01), Curiel et al.
patent: 5534423 (1996-07-01), Plasson et al.
patent: 5543328 (1996-08-01), McClelland et al.
patent: 5547932 (1996-08-01), Curiel et al.
patent: 5552311 (1996-09-01), Sorscher et al.
patent: 5559099 (1996-09-01), Wickham et al.
patent: 5571698 (1996-11-01), Ladner et al.
patent: 5622699 (1997-04-01), Ruoslahti et al.
patent: 5712136 (1998-01-01), Wickham et al.
patent: 5731190 (1998-03-01), Wickham et al.
patent: 5756086 (1998-05-01), McClelland et al.
patent: 5770442 (1998-06-01), Wickham et al.
patent: 5837511 (1998-11-01), Falck-Pedersen et al.
patent: 5846782 (1998-12-01), Wickham et al.
patent: 5849561 (1998-12-01), Falck-Pedersen
patent: 5856152 (1999-01-01), Wilson et al.
patent: 5871727 (1999-02-01), Curiel
patent: 5871982 (1999-02-01), Wilson et al.
patent: 5877011 (1999-03-01), Armentano et al.
patent: 5922315 (1999-07-01), Roy
patent: 5994128 (1999-11-01), Fallaux et al.
patent: 6007806 (1999-12-01), Lathe et al.
patent: 6033908 (2000-03-01), Bout et al.
patent: 6057155 (2000-05-01), Wickham et al.
patent: 6100086 (2000-08-01), Kaplan et al.
patent: 6127525 (2000-10-01), Crystal et al.
patent: 6287857 (2001-09-01), O'riordan et al.
patent: 6306652 (2001-10-01), Fallaux et al.
patent: 6486133 (2002-11-01), Herlyn et al.
patent: 6492169 (2002-12-01), Vogels et al.
patent: 6669942 (2003-12-01), Perricaudet et al.
patent: 1016726 (1998-12-01), None
patent: 1067188 (1999-07-01), None
patent: 1020529 (1999-11-01), None
patent: WO 91/00360 (1991-01-01), None
patent: WO 91/05805 (1991-05-01), None
patent: WO 91/05871 (1991-05-01), None
patent: WO 92/02553 (1992-02-01), None
patent: WO 92/13081 (1992-08-01), None
patent: WO 93/03769 (1993-03-01), None
patent: WO 93/06223 (1993-04-01), None
patent: WO 93/07282 (1993-04-01), None
patent: WO 93/07283 (1993-04-01), None
patent: WO 94/08026 (1994-04-01), None
patent: WO 94/10323 (1994-05-01), None
patent: WO 94/11506 (1994-05-01), None
patent: WO 94/15644 (1994-07-01), None
patent: WO 94/17832 (1994-08-01), None
patent: WO 94/24299 (1994-10-01), None
patent: WO 94/26915 (1994-11-01), None
patent: WO 95/05201 (1995-02-01), None
patent: WO 95/06745 (1995-03-01), None
patent: WO 95/14785 (1995-06-01), None
patent: WO 95/16037 (1995-06-01), None
patent: WO 95/21259 (1995-08-01), None
patent: WO 95/26412 (1995-10-01), None
patent: WO 95/27071 (1995-10-01), None
patent: WO 96/13598 (1995-10-01), None
patent: WO 95/31187 (1995-11-01), None
patent: WO 95/31566 (1995-11-01), None
patent: WO 96/00326 (1996-01-01), None
patent: WO 96/00790 (1996-01-01), None
patent: WO 96/26281 (1996-02-01), None
patent: WO 96/07739 (1996-03-01), None
patent: WO 96/10087 (1996-04-01), None
patent: WO 96/12030 (1996-04-01), None
patent: WO 96/13597 (1996-05-01), None
patent: WO 96/14837 (1996-05-01), None
patent: WO 96/17073 (1996-06-01), None
patent: WO 96/18740 (1996-06-01), None
patent: WO 96/24453 (1996-08-01), None
patent: WO 96/35798 (1996-11-01), None
patent: WO 97/00326 (1997-01-01), None
patent: WO 97/12986 (1997-04-01), None
patent: WO 97/20575 (1997-06-01), None
patent: WO 97/38723 (1997-10-01), None
patent: WO 98/07865 (1998-02-01), None
patent: WO 98/11221 (1998-03-01), None
patent: WO 98/13499 (1998-04-01), None
patent: WO 98/22609 (1998-05-01), None
patent: WO 98/32842 (1998-07-01), None
patent: WO 98/40509 (1998-09-01), None
patent: WO 98/49300 (1998-11-01), None
patent: WO 98/50053 (1998-11-01), None
patent: WO 99/32647 (1999-07-01), None
patent: WO 99/47180 (1999-09-01), None
patent: WO 99/55132 (1999-11-01), None
patent: WO 99/58646 (1999-11-01), None
patent: WO 00/03029 (2000-01-01), None
patent: WO 00/24730 (2000-05-01), None
patent: WO 00/31285 (2000-06-01), None
patent: WO 00/52186 (2000-09-01), None
patent: WO 00/70071 (2000-11-01), None
patent: WO 01/04334 (2001-01-01), None
patent: WO 01/90158 (2001-11-01), None
patent: WO 02/24730 (2002-03-01), None
patent: WO 02/27006 (2002-04-01), None
Crawford-Miksza, Journal of Virology, vol. 70, pp. 1836-1844, 1996.
IM Verma et al., Nature, “Gene therapy-promisses, problems and prospects,” Sep. 1997, vol. 389, pp. 239-242.
Merriam-Webster Dictionary(on line) retrieved from the internet<URL:http://www. m-w.com/cgi-bin/dictionary, “derive,”2002.
S Gurunathan et al., American Association of Immunologists, “CD40 Ligand/Trimer DNA Enhances Both Humoral and Cellular Immune Responses and Induces Protective Immunity to Infectious and Tumor Challenge,” 1998, 161:4563-4571.
T-L Chiu et al., Folding & Design, “Optimizing energy potentials for success in protein tertiary structure prediction,” May 1998, 3: 223-228.
JT Ngo et al., The Protein Folding Problem and Tertiary Structure Prediction, “Computational Complexity, Protein Structure Prediction, and the Levinthal Paradox,” 1994, Merz et al.(editors), Birkhauser, Boston,MA, pp. 433 and 492-495.
WF Anderson, Nature, “Human gene therapy,” Apr. 1998, vol. 392, pp. 25-30.
Basler et al.; Sequence of the immunoregulatory early region 3 and flanking sequences of adenovirus type 35, 1996, Gene 170: 249-254.
Jolly; Viral vector systems for gene therapy, 1994, Cancer Gene Therapy, vol. 1, No. 1: 51-64.
Stevenson et al.; Selective Targeting of Human Cells by a Chimeric Adenovirus Vector Containing a Modified Fiber Protein, 1997,Journal of Virology, vol. 71: 4782-4790.
Abrahamsen et al., “Construction of an Adenovirus Type 7a E1A Vector,” Journal of Virology, Nov. 1997, pp. 8946-8951 vol. 71, No. 11.
Albiges-Rizo et al., “Human Adenovirus Serotype 3 Fiber Protein,” Journal of Biological Chemistry, 266(6), 3961-3967 (1991).
Athappilly et al., “The Refined Crystal Structure of Hexon, the Major Coat Protein of Adenovirus Type 2, at 2•9 A Resolution,” J. Mol. Biol. (1994) 242, 430-455.
Bai et al., “Mutations That Alter an Arg-Gly-Asp (RGD) Sequence in the Adenovirus Type 2 Penton Base Protein Abolish Its Cell-Rounding Activity and Delay Virus Reproduction in Flat Cells,” Journal of Virology, 67(9), 5198-5205 (1993).
Bailey et al., “Phylogenetic Relationships among Adenovirus Serotypes,” Virology, 205, 439-452 (1994).
Ball-Goodrich et al., “Parvoviral Target Cell Specificity: Acquisition of Fibrotropism by a Mutant of the Lymphotropic Strain of Minute Virus of Mice Involves Multiple Amino Acid Substitutions within the Capsid,
Bout Abraham
Havenga Menzo
Vogels Ronald
Crucell Holland B.V.
Priebe Scott D.
TraskBritt
Whiteman Brian
LandOfFree
Serotype of adenovirus and uses thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Serotype of adenovirus and uses thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Serotype of adenovirus and uses thereof will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3374601