Serotype 2 Marek's disease vaccine

Drug – bio-affecting and body treating compositions – Lymphokine

Patent

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424 93, 4351721, 435237, 435948, 935 63, 935 65, 935 70, A61K 3912, A61K 3700, C12N 1500, C12N 708, C12R 191

Patent

active

048957186

ABSTRACT:
A serotype 2 Marek's disease vaccine comprising a cloned strain designated as 301B/1 has been derived from a field isolate. This strain is characterized by superior levels of replicative ability and protectivity in chickens as compared to existing commercial serotype 2 strains, and it is virtually nonpathogenic. 301B/1 is particularly useful in the formulation of highly efficacious bivalent and polyvalent vaccines.

REFERENCES:
patent: 4160024 (1979-07-01), Schat et al.
Paoletti et al (1984), PNAS, 81:193.
R. L. Witter, "Characteristics of Marek's Disease Viruses Isolated from Vaccinated Commercial Chicken Flocks: Association of Viral Pathotype with Lymphoma Frequency," Avian Dis. 27(1): 113-132 (Jan.-Mar. 1983).

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