Serotonin and norepinephrine uptake inhibitors

Details Serotonin and norepinephrine uptake inhibitors Serotonin and norepinephrine uptake inhibitors

1988-12-14

1990-02-20

Siegel, Alan

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514336, 514343, 514351, 514369, 514372, 514422, 514424, 514444, 514461, 514649, 546280, 546281, 546283, 546284, 546300, 548189, 548213, 548517, 548527, 548550, 549 59, 549 60, 549 65, 549472, 549479, 564341, A61K 3138, A61K 3134, C07D40900, C07D33332

Patent

active

049027107

ABSTRACT:
The present invention provides propanamines, substituted at the 3-position of the propanamine chain with a thio, sulfinyl or sulfonyl moiety, which are capable of selectively inhibiting the uptake of serotonin and norepinephrine.

REFERENCES:
patent: 4018895 (1977-04-01), Molloy et al.
patent: 4194009 (1980-03-01), Molloy et al.
patent: 4314081 (1982-02-01), Molloy et al.
patent: 4329356 (1982-05-01), Holland
patent: 4686309 (1987-08-01), Barriere et al.
Wolff, Burger's Medicinal Chemistry, Part III, 4th ed., pp. 1008, 1014-1017, 1038-1039 and 1041-1043 (1981).

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