Serotonin agonist in combination with a tachykinin receptor anta

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514415, A61K 31405, A61K 31445

Patent

active

057444820

ABSTRACT:
Methods for the treatment or prevention of migraines comprising administering to a mammal in need thereof a combination of a tachykinin receptor antagonist and a serotonin agonist are disclosed. The administration may be concurrent or sequential, with either of the two activities being administered first.

REFERENCES:
Shepheard et al., Br. J. Pharm., 108(1) 11-12 (1993).
Oliver et al., Arzneim.-Forsch./Drug Res., 44(II) 925-928, Aug. 1994.

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