Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1991-07-30
1993-02-23
Springer, David B.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
548496, C07D20920, A61K 31405
Patent
active
051891794
ABSTRACT:
The present invention is directed to a new class of serotonin 5HT.sub.1A agonists.
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Hamel et al., Br. J. Pharmacol, (1991), 102, pp. 227-233; Contractile 5HT.sub.1 receptors in human isolated pial arterioles: correlation with 5-HT.sub.1D binding sites.
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European Journal of Pharmacology, 163, (1989) 133-136, Peroutka, et al.; Sumatriptan (GR 43175) interacts selectively with 5-HT.sub.1B and 5-HT.sub.1D binding sites.
Bernotas Ronald C.
Dudley Mark W.
McDonald Ian A.
Sprouse Jeffrey S.
Dixon J. Michael
Merrell Dow Pharmaceuticals Inc.
Springer David B.
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