Serotonin 5HT.sub.1A agonistic method

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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A61K 31405, A61K 3140

Patent

active

055591434

ABSTRACT:
The present invention is directed to a new class of serotonin 5HT.sub.1A agonists.

REFERENCES:
patent: 2725386 (1955-11-01), Bovei et al.
patent: 4614807 (1986-09-01), Flaugh et al.
Marinus O. den Boer, et al, Br. J. Pharmacol (1991), 102, pp. 323-330, Role of 5HT.sub.1 -like receptors in the reduction of porcine cranial arteriovenous anastomotic shunting by sumatriptan.
Saxena, et al, TIPS, May 1989, vol. 10, pp. 200-204; 5HT.sub.1 -like receptor agonists and the pathophysiology of migraine.
Hamel et al., Br. J. Pharmacol, (1991), 102, pp. 227-233; Contractile 5HT.sub.1 receptors in human isolated pial arterioles: correlation with 5-HT.sub.1D binding sites.
Edward E. Schweizer, et al.; Psychopharmacology Bulletin, vol. 22, No. 1, 1986, pp. 183-185; Open Trial of Buspirone in the Treatment of Major Depressive Disorder.
European Journal of Pharmacology, 180 (1990) pp. 339-349, Dreteler, et al.; Comparision of the cardiovascular effects of the 5-HT1A receptor agonist flexinoxan with that of 8-OH-DPAT in the rat.
European Journal of Pharmacology, 182 (1990) 63-72, Connor, et al.; Cardiovascular effects of 5HT.sub.1a receptor agonists injected into the dorsal raphe nucleus of conscious rats.
European Journal of Pharmacology, 163, (1989) 133-136, Peroutka, et al; Sumatriptan (GR 43175) interacts selectively with 5-HT.sub.1B and 5-HT.sub.1D binding sites.

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