Multicellular living organisms and unmodified parts thereof and – Method of using a transgenic nonhuman animal in an in vivo...
Patent
1998-08-11
2000-05-09
Crouch, Deborah
Multicellular living organisms and unmodified parts thereof and
Method of using a transgenic nonhuman animal in an in vivo...
800 18, 800 21, 800 9, 4351721, 4351723, 435325, 435455, 536 235, C12N 500, C12N 1512, A01K 67027, G01N 3315, C07H 2104
Patent
active
060606428
ABSTRACT:
The present invention features transgenic mice models for gene function, wherein the transgenic mice are characterized by having altered serotonin 5-HT6 receptor gene function. The transgenic mice may be either homozygous or heterozygous for a disruption in the endogenous 5-HT6 gene. Transgenic mice homozygous for a disruption in the endogenous 5-HT6 gene display a phenotype of increased anxiety behavior including diminished investigation of foreign objects and an elevation in stretched attend postures.
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Brennan Thomas J.
Tecott Laurence H.
Borden Paula A.
Crouch Deborah
Kerr Janet M.
Sherwood Pamela J.
The Regents of the University of California
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