Serotonergic substituted piperazinyl tetralins

Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...

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544357, 544392, 544393, C07D40302, C07D29504

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active

048452211

ABSTRACT:
The compounds ##STR1## in which R.sub.1 is hydroxy, alkoxy of 1 to 6 carbon atoms, amino, alkylamino of 1 to 6 carbon atoms, dialkylamino where each alkyl substituent contains 1 to 6 carbon atoms, or alkanoylamino of 2 to 6 carbon atoms;

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Sandoz, Inc. Chem. Abst. 90-204143s.
Smith et al., Chem. Abst. 105-78960u.
Derwent Abstract No. 37505S-B, Netherlands, Pat. No. 7,017,031, 11/69; N-(Heterozryl)Piperazinylalkyl Derivs.
Derwent Abstract No. 85-000957/01, DE 3,321,969-12/84-New 1-pyrimidyl-4-Subst. piperazine derivs. with CNS e.g. anxiolytic and antidepressant activities.
Derwent Abstract No. 85-250735/41, U.S. Pat. No. 4,640.922-3/87; N-Alkoxy:carbonyl-5-alkoxy:carbonyl di:hydro:pyrimidine cpds. useful in treating cardiovascular disorders, e.g. as hypotensives.

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