Serine-threonine phosphatase protein of a parasitic organism...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving transferase

Reexamination Certificate

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C435S194000, C424S094600

Reexamination Certificate

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06949352

ABSTRACT:
The present invention relates to a serine-threonine phosphatase protein of a parasitic organism of the Apixomplexa phylum and uses thereof.

REFERENCES:
Wester's II New Riverside Dictionary (1994) (houoghton Mifflin: Boston MA) p. 762 and 927.
C.B. Mamoun, et al., Molecular Microbiology, vol. 39, No. 4, pp. 973-981, XP-002229525, “Plasmodium Protein Phosphatase 2C Dephosphorylates Translation Elongation Factor 1β and Inhibits its PKC-Mediated Nucleotide Exchange Activity in Vitro”, Feb. 2001.
C.B. Mamoun, et al., The Journal of Biological Chemistry, vol. 273, No. 18, pp. 11241-11247, XP-002229526, “Identification and Characterization of an Unusual Double Serine/Threonine Protein Phosphatase 2C in the Malaria Parasite Plasmodium Falciparum”, May 1, 1998.
O. Poupel, et al., Molecular Biology of the Cell, vol. 11, pp. 355-368, XP-002229527, “Toxoflin, A Novel Actin-Binding Protein from Toxoplasma Gondii, Sequesters Actin Monomers and Caps Actin Filaments”, Jan. 2000.
V. D. Delorme, Database EMBL Online!, Thesis 2002 Dpt. Biol. Sci. Univ. VII, an Q8WPN9, p. 1, XP-002229528, “Serine-Threonine Phosphatase 2C. Toxoplasma Gondii”, Mar. 1, 2002.
V. Delorme, et al., Molecular Biology of the Cell, vol. 14, pp. 1900-1912, “Actin Dynamics is Controlled by a Casein Kinase II and Phosphatase 2C Interplay on Toxoplasma Gondii Toxofilin”, May 2003.

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