Serine/threonine kinase and nucleic acids encoding same

Details Serine/threonine kinase and nucleic acids encoding same Serine/threonine kinase and nucleic acids encoding same

1994-06-02

1997-07-22

Walsh, Stephen G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 2431, 536 241, 435194, 4353201, 435 691, 435325, 435348, 435419, 435365, 435358, 435367, 435352, 530350, 530324, C07K 14705, C07K 1400, C12N 510, C12N 1552

Patent

active

056505019

ABSTRACT:
A serine/threonine kinase protein which is associated with mitotic and meiotic cell division and which is characterized by having a kinase domain in its N-terminus and three PEST regions in the C-terminus, and nucleic acid molecules encoding the protein. Diagnostic and therapeutic methods using the serine/threonine kinase protein and nucleic acid molecules are also described.

REFERENCES:
patent: 5451518 (1995-09-01), Kolesnick
Llamazares, S. et al., Genes & Dev. 5:2153-2165, 1991.
Kitada, K. et al, Mol. and Cell. Biol. 13(7):4445-4457, 1993.
Fenton, B. & Glover, D. M., Nature 363:637-640, 1993.
Sharon, G. & Simchen, G., Genet. 125:475-485, 1990.
Schild, D. & Byers, B., Genet. 96:859-876, 1980.
Simmons, D. L. et al., Mol. and Cell. Biol. 12(9):4164-4169, 1992.
Clay, F. J. et al., Proc. Natl. Acad. Sci. USA 90:4882-4886, 1993.
van den Heuvel, S. and Harlow E., Science 262:2050-2054, 1993.
Dennis, J. W. (1986) Cancer Res. 46:4594-4600.
Heffernan, M. & Dennis, J. W. (1991) Nucleic Acids Research 19(1):85-92.
Padgett, R. A., et al., Ann. Rev. Biochem. 55, 1119-1150, 1986.
Kozak, M. (1986) Cell 44:283-292.
Shaw, G. & Kamen, R. (1986) Cell 46:659-667.
Hanks, S. K. & Quinn, A. M. (1991) Methods. Enzymol. 200:38-63.
Rogers, S., Wells, R. & Rechsteiner, M. (1986) Science 234:364-368.
Stein, R., Mori, N., Matthews, K., Lo, L.-C. & Anderson, D. J. (1988) Neuron 1, 463-476.
Hamanaka et al, "Cloning and Characterization of Human and Murine Homologues of the Drosophila polo Seriue & Threonine Kinase", Cell Grwth. Diff. 5:249-257 (Mar. 1994).
Kruger et al, "Cloning and Characterization of . . . PKCs . . ." J. Neurosci. 11(8):2303-2318.
Golsteyn et al, "Cell cycle analysis and chromosomal localization of human plkl . . .", J. Cell Sci. 107:1509-1517 (Jun. 1994).

Affiliated with

Also associated with

Rating

Serine/threonine kinase and nucleic acids encoding same does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Serine/threonine kinase and nucleic acids encoding same, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Serine/threonine kinase and nucleic acids encoding same will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1560670