Serine protease variants having amino acid deletions and...

Details Serine protease variants having amino acid deletions and... Serine protease variants having amino acid deletions and...

2005-06-21

2005-06-21

Achutamurthy, Ponnathapura (Department: 1652)

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Hydrolase

C435S220000, C435S221000, C435S222000, C435S471000, C510S392000, C424S094640, C536S023200

Reexamination Certificate

active

06908757

ABSTRACT:
The present invention relates to variants of serine proteases having decreased immunogenicity relative to their corresponding wild-type proteases. More particularly, the present invention relates to variants having a modified amino acid sequence of a wild-type amino acid sequence, wherein the modified amino acid sequence comprises a deletion and, optionally, a substitution of one or more specifically identified positions corresponding to subtilisin BPN′. The invention further relates to mutant genes encoding such variants and cleaning and personal care compositions comprising such variants.

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