Serine protease mutants of the chymotrypsin superfamily resistan

Details Serine protease mutants of the chymotrypsin superfamily resistan Serine protease mutants of the chymotrypsin superfamily resistan

1989-11-13

1996-08-27

Fleisher, Mindy

Chemistry: molecular biology and microbiology

Treatment of micro-organisms or enzymes with electrical or...

Modification of viruses

4353201, 435212, 435 691, 530380, 536 232, 536 235, C12N 1501, C12N 1563, C12N 950, C07H 2104

Patent

active

055500420

ABSTRACT:
The present invention relates to serine protease mutants of the chymotrypsin superfamily that are resistant to inhibition by their cognate inhibitors, and genes that encode the same. The present invention also relates to serine protease inhibitor mutants that inhibit the serine protease mutants of the present invention, and genes that encode the same. The serine protease, mutants and serine protease inhibitor mutants are useful as, e.g., pharmacological agents.

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