Serine protease inhibitors--N-substituted derivatives

Details Serine protease inhibitors--N-substituted derivatives Serine protease inhibitors--N-substituted derivatives

1997-12-04

1999-12-14

Russel, Jeffrey E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 19, 530331, 548128, 548131, 548136, 548143, 5482668, A61K 3805, A61K 3806, C07K 5062, C07K 508

Patent

active

060018119

ABSTRACT:
The present invention relates to oxadiazole, thiadiazole, and triazole peptoids that are inhibitors of serine protease, specifically human neutrophil elastase; which proteases are useful in treatment of adult respiratory distress syndrome, septic shock, and multiple organ failure.

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