Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2006-02-14
2006-02-14
Guzo, David (Department: 1636)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S007100, C530S387100
Reexamination Certificate
active
06998245
ABSTRACT:
There are provided proteins having the amino acid sequences represented by SEQ ID NOS: 2 and 4; proteins having amino acid sequences derived from these amino acid sequences by deletion, substitution or addition of one to several amino acids; and nucleotide sequences encoding the same; transgenic non-human animals with altered expression level of a serine protease BSSP5; an antibody against BSSP5; and a method for detecting BSSP5 in a specimen by using the antibody. The BSSP5 provied by the present invention can be used for treating and diagnosing various diseases such as Alzheimer's disease (AD), epilepsy, cancer, inflammation, sterility and prostatic hypertropy and detecting pancreatitis in various tissues including brain, prostate gland, placenta, pancreas and spleen.
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Kominami Katsuya
Mitsui Shinichi
Okui Akira
Uemura Hidetoshi
Yamaguchi Nozomi
Browdy and Neimark PLLC
FUSO Pharmaceutical Industries, Ltd.
Guzo David
Sullivan Daniel M.
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