Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1995-02-08
1997-08-26
Robinson, Douglas W.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
435 698, 4351723, 435219, 4353201, 536 231, 935 14, 935 36, 935 48, C12P 2106, C07H 2104, C12N 1563, C12N 950
Patent
active
056610009
ABSTRACT:
The present invention offers the serine protease exhibiting a biological activity which a polypeptide having an amino acid sequence shown in FIG. 1 shows, the serine protease precursor where a cleavable peptide or signal peptide connects with the N-terminal of the said serine protease, and the gene encoding them. The serine protease being useful in medical treatment fields can be manufactured in large quantities by the present invention.
Moreover, the present invention offers the DNA sequence coding a transcription controlling region contained in the chromosomal gene of the serine protease of a human myeloid cell. This sequence is the transcription controlling region being necessary for the gene expression being specific to a human leukocyte or erythrocyte.
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Aoki Yosuke
Nakamura Haruji
Naruto Masanobu
Okano Kiyoshi
Shimizu Hirohiko
Miller Austin R.
Robinson Douglas W.
Toray Industries Inc.
Wai Thanda
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