Serine carboxypeptidase hx (SCPhx) and compositions thereof

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C435S069100, C435S071100, C435S183000, C435S212000, C435S219000, C530S350000, C530S412000, C530S413000

Reexamination Certificate

active

07074571

ABSTRACT:
The invention concerns GENSET polynucleotides and polypeptides. Such GENSET products may be used as reagents in forensic analyses, as chromosome markers, as tissue/cell/organelle-specific markers, in the production of expression vectors. In addition, they may be used in screening and diagnosis assays for abnormal GENSET expression and/or biological activity and for screening compounds that may be used in the treatment of GENSET-related disorders.

REFERENCES:
patent: WO 99/14234 (1999-03-01), None
patent: WO 99/53051 (1999-10-01), None
patent: WO 01/53455 (2001-07-01), None
patent: WO 01/53455 (2001-07-01), None
OM protein search, Accession No. AAY64665, Feb. 1, 2000.
Ngo et al. The Protein Folding Problem and Tertiary Structure Prediction, 1994, Mertz et al (ed). Birkhauser, Boston, MA, pp. 433 and 492-495.
Skolnick et al. Trends in Biotechnology, 2000, 18(1): 34-39.
Kim, S.,et al.; “Regulation of Plasminogen Receptor Expression on Monocytoid Cells by B1-Integrin-dependent Cellular Adherence to Extracellular Matrix Proteins”; The Journal of Biological Chemistry; vol. 271, No. 39, Issue of Sep. 27, pp. 23761-23767, 1996; The American Society for Biochemistry & Molecular Biology, Inc.
Mao, S., et al.; “Characterization of Plasmin-mediated Activation of Plasma Procarboxypeptidase B”; The Journal of Biological Chemistry, vol. 274, No. 49, Issue of Dec. 3, pp. 35046-35052, 1999; The American Society for Biochemistry and Molecular Biology, Inc.
Remington, James S.; “Serine carboxypeptidases: a new and versatile family of enzymes”; Current Opinion in Biotechnology 1993, 4:462-468; Current Biology Ltd.; ISSN 0958-1669.
Fruebis, J., et al.; “Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice”; PNAS, Feb. 13, 2001, vol. 98, No. 4; 2005-2010.
Hamstra, D.A. et al.; “Expression endogenously activated secreted or cell surface carboxypeptidase A sensitizes tumor cells to methotrexate-a-peptide prodrugs”; Cancer Research 50, 657-665, Feb. 1, 2000.
Matsumoto, A., et al.; “A novel carboxypeptidase B that processes native B-amyloid precursor protein is present in human hippocampus”; European Journal of Neuroscience, vol. 12, pp. 227-238, 2000; European Neuroscience Association.
Herren, T., et al.; “Regulation of plasminogen binding to neutrophils”; Blood, Frb. 15, 2001, vol. 97, No. 4, pp. 1070-1078; The American Society of Hematology.
Du, J., et al.; “Key peptide processing enzymes are expressed by breast cancer cells”; Cancer Letters 165 (2001) 2111-218, 0304-3835/00; Elsevier Science Ireland Ltd.
Napier, M.P., et al.; “Antibody-directed Enzyme Prodrug Therapy: Efficacy and Mechanism of Action in Colorectal Carcinoma”; Clinical Cancer Research, vol. 6, 765-772, Mar. 2000.
Shi, P.T., et al.; “The solid-phase synthesis of methotrexate-alpha-peptides”;Yao Xue Xue Bao, 1997; 32(2):106-9; Abstract, PMID: 11243192 [PubMed—indexed for MEDLINE].
Accession No. Q96A94; Strausberg, R.
Accession No. Q9HB40; Cho, et al.; “Cloning of novel serine carboxypeptidase precursor”.
Accession No. AAM25395; Tang, et al.; “Isolated human polynucleotides encoding polypeptides, useful for the treatment and diagnosis of e.g. cancer, ulcers and HIV infection”.
Celera Protein Accession No. hCP1766200.
Celera Protein Accession No. hCP46705.2.
Celera Protein Accession No. hCP1766203.
Accession No. AAY05768; Fong, et al.; “Composition containing human polypeptides with anti-angiogenic activity”.
Accession No. AAY13387; Chen, et al.; “New isolated human genes and polypeptides used in, e.g. treatment of gastrointestinal ulceration”.
Accession No. AAY88378; Fong, et al.; “A composition comprising PRO230, PRO216 or PRO302 polypeptides, agonists or antagonists useful for promotion or inhibition of cardiovascularisation, angiogenesis or endothelialisation in mammals”.
Accession No. AAE06595; Kato, et al.; “Human proteins with hydrophobic domains and the nucleic acids encoding them, useful for preventing diagnosing and treatinge.g. cancer, Alzheimer's and inflammation”.
Accession No. AAB93913; Ota, et al.; “Primer sets for synthesizing polynucleotides, particularly the 5602 full-length cDNAs defined inthe specification, and for the detection and/or diagnosis of the abnormality of theproteins encoded by the full-length cDNAs”.
Accession No. AAB20341; Fong, et al.; “Composition comprising a PRO230, PRO216 or PRO302 polypeptide, agonist or antagonist from promoting or inhibiting angiogenesis and/or cardiovascularisation in mammals”.
Accession No. AAB80255; Ashkenazi, et al.; “Sixty one nucleic acids encoding PRO polypeptides which are useful in the treatment of skin diseases (e.g. psoriasis), cancers (e.g. lung squamous cell carcinoma) and neurodegenerative diseases (e.g. Alzheimer's disease)”.
Accession No. CAC51169; Kato, et al.; “Human proteins having hydrophobic domains and dnas encoding these proteins”.
Accession No. AF282618; Cho, et al.; “Cloning of novel serine carboxypeptidase precursor”.
Accession No. AK027373; Isogai, et al.; “NEDO human cDNA sequencing progject”.
Accession No. AX191563; Kato, et al.; “Human proteins having hydrophobic domains and dnas encoding these proteins”.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Serine carboxypeptidase hx (SCPhx) and compositions thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Serine carboxypeptidase hx (SCPhx) and compositions thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Serine carboxypeptidase hx (SCPhx) and compositions thereof will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3586817

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.