Serial derivatization of peptides for de novo sequencing...

Details Serial derivatization of peptides for de novo sequencing... Serial derivatization of peptides for de novo sequencing...

2008-05-13

2008-05-13

Gitomer, Ralph (Department: 1657)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Reexamination Certificate

active

07371514

ABSTRACT:
Serial derivatization by chemical reactions of analytes for mass spectrometry is disclosed. The derivatizations enhance the use of MS techniques for analyzing protein samples, particularly when the sequence of a polypeptide is determined by tandem MS/MS. Accurate mass analysis techniques are described for use in sequencing polypeptides, together with the use of sequencing data in protein analysis.

REFERENCES:
patent: 5821063 (1998-10-01), Patterson et al.
patent: 2003/0032056 (2003-02-01), Palmgren et al.
patent: WO 00/43792 (2000-07-01), None
patent: WO 02/08767 (2002-01-01), None
patent: WO 02/095419 (2002-11-01), None
patent: WO 03/056299 (2003-07-01), None
Kislinger et al. Curr Opin Mol Ther 2003, 5(3):285-293.
Aebersold and Mann, 2003, Nature 422:198-207.
Aebersold and Goodlett, Chem. Rev. 101:269-295, 2001.
Cagney and Emili, Nat. Biotech. 20: 163-170, 2002.
Cardenas, et al., Rapid Comm. Mass Spectrum. 11:1271-1278, 1997.
Chen, et al., Journal of Computational Biology, 8(6), 571-583, 2001.
Claverol, et al., Mol. Cell. Proteomics 2: 483-493, 2003.
Cramer and Corless, Rapid Comm. in Mass Spectrom. 15: 2058-2066, 2001.
Dancik, et al., Journal of Computational Biology, 6, 327-342, 1999.
Eng, et al., J. Am. Soc. Spectrom., 5:976-989, 1994.
Ficarro, Scott B. et al., Phosphoproteome Analysis by Mass Spectrometry and its Application toSaccharomyces cerevisiae, Nature Biotechnology, 2002; 19:301-305.
Goodlett, David R. et al., Differential Stable Isotope Labeling of Peptides for Quantitation and de novo Sequence Derivation, Rapid Commun. Mass Spectrom, 2001; 15:1214-1221.
Gu et al., J. Am. Soc. Mass Spectrom. 14: 1-7, 2003.
Hunt, et al., PNAS 83: 6233, 1986.
Keough, T. et al., A Method for High-Sensitivity Peptide Sequencing Using Postsource Decay Matrix-Assisted Laser Desorption Ionization, Proc. Natl. Acad. Sci., 96:7131-7136, Jun. 1999.
Keough, T. et al., “Atmospheric Pressure Matrix-Assisted Laser Desorption/Ionization Ion Trap Mass Spectrometry of Sulfonic Acid Derivatized Tryptic Peptides,” Rapid Commun. Mass Spectrom 2001, 15: 2227-2239.
MacCoss et al., PNAS 99: 7900-7905, 2002.
Mann, et al., 2001, Ann. Rev. Biochemistry 70:437-473.
Mann and Jensen, Nat. Biotech. 21: 255-261, 2003.
Mann & Wilm, Anal. Chem., 66:4390-4399, 1994.
Munchbach et al., Anal. Chem. 72: 4047-4057, 2000.
Person, et al. Chem. Res. Toxicol 16: 598-608, 2003.
Sze, Siu Kwan et al., “Top-Down Mass Spectrometry of a 29-kDa Protein for Characterization of any posttranslational modification to within one residue” PNAS 99: 1774-1779, 2002.
Taylor and Johnson, Rapid Communications in Mass Spectrometry, 11, 1067-1075, 1997.
Uttenweiler-Joseph et al., Proteomics 1: 668-682, 2001.
Zabrouskov et al., Mol. Cell. Proteomics 2:1253-1260, 2003.
Bonetto, Valentina et al., “C-Terminal Sequence Analysis of Peptides and Proteins Using Carboxypeptidases and Mass Spectrometry after Derivatization of Lys and Cys Residues”, Analytical Chemistry, vol. 69, No. 7, 1997, pp. 1315-1319.
Peters, Eric C. et al., “A Novel Multifunctional Labeling Reagent for Enhanced Protein Characterization with Mass Spectrometry”, Rapid Communications in Mass Spectrometry, vol. 15, No. 21, 2001, pp. 2387-2392.
Liu, Hongji et al., “Homogeneous Fluorescent Derivatization of Large Proteins”, Journal of Chromatography A, vol. 927, No. 1-2, 2001, pp. 77-89.
Kuroda, N. et al., “Solution-Phase Automated Synthesis of Tripeptide Derivatives”, Chem. Pharm. Bull., vol. 49, No. 9, pp. 1138-1146, 2001.
Tomlinson, Andy J. et al., “A Strategy for Sequencing Peptides from Dilute Mixtures at the Low Femtomole Level Using Membrane Preconcentration-Capillary Electro-Phoresis-Tandem Mass Spectrometry (mPC-CE-MS/MS)”, J. Liquid Chromatography, vol. 18, No. 18-19, pp. 3591-3615, 1995.
Falick, A.M. et al., “Derivation of Hydrophilic Peptides for Liquid Secondary Ion Mass Spectrometry at the Picomole Level”, Analytical Biochemistry, vol. 182, No. 1, pp. 165-169.
Communication from EPO dated Feb. 8, 2006, enclosing EP Search Report for EP Application No. EP 05013477, counterpart to U.S. Appl. No. 10/892,870.

Affiliated with

Also associated with

Rating

Serial derivatization of peptides for de novo sequencing... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Serial derivatization of peptides for de novo sequencing..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Serial derivatization of peptides for de novo sequencing... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2776189