Sequestering subunit and related compositions and methods

Details Sequestering subunit and related compositions and methods Sequestering subunit and related compositions and methods

2003-09-22

2010-10-19

Azpuru, Carlos A (Department: 1615)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Capsules

C424S463000, C424S464000, C424S474000

Reexamination Certificate

active

07815934

ABSTRACT:
A sequestering subunit comprising an aversive agent and a blocking agent, wherein the blocking agent substantially prevents release of the aversive agent from the sequestering subunit in the gastrointestinal tract for a time period that is greater than 24 hours; a composition comprising a sequestering subunit and a therapeutic agent in releasable form, wherein, optionally, the mechanical fragility of the sequestering subunit is the same as the mechanical fragility of the therapeutic agent in releasable form; a capsule or tablet comprising a sequestering subunit and a therapeutic agent; and a method of preventing abuse of a therapeutic agent.

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