Sequences of an I h ion channel and use thereof

Details Sequences of an I h ion channel and use thereof Sequences of an I h ion channel and use thereof

2006-08-01

2009-06-16

Chernyshev, Olga N (Department: 1649)

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

C435S069100

Reexamination Certificate

active

07547763

ABSTRACT:
The present invention relates to an isolated or purified human nucleic acid, preferably a DNA, comprising a nucleotide sequence encoding an Ihion channel. The invention further relates to a vector comprising the isolated or purified nucleic acid, a host cell comprising the vector, and a composition comprising the isolated or purified nucleic acid and a carrier therefore. The invention also provides a polypeptide or protein encoded by the nucleic acid, and a method of treating a mammal for a cardiovascular disorder.

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patent: WO 99/18941 (1999-04-01), None
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Bucci et al.,J. Gen. Physiol., 120: 1-13 (2002).
Chaplan et al.,J. Neurosci., 23(4):1169-1178 (2003).
Gauss et al.,Nature, 393(11): 583-587 (1998).
Hiller et al., Emhum Database Engry HSN72770, Accession No. N72770, XO0209146 (1996).
Jenkins et al.,PCR Methods and Applications, 3(5): S77-82 (1994).
Ludwig et al.,Nature, 393(11) 587-591 (1998).
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Santoro et al.,GenBankAccession No. AF064877 (May 29, 1998).
Seifert et al.,PNAS USA, 96: 9391-9396 (1999).

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