Sequences for production of 2,4-Diacetylphloroglucinol and metho

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

435183, 435195, 4352523, 4353201, 536 232, 536 237, 536 2432, 530350, C12D 2102, C07H 2104, C12N 121, C12N 914

Patent

active

059552980

ABSTRACT:
DNA sequences which function specifically in the synthesis of 2,4-diacetylphloroglucinol (Phl) are described. The sequences include phl genes which encode phl gene proteins and coding and regulatory sequences for production of Phl as well as sequences containing phl genes, which sequences have the capability of conferring or enhancing Phl biosynthetic capability in bacterial strains. The transformed strains are useful as biocontrol agents against fungal pathogens.

REFERENCES:
patent: 5518901 (1996-05-01), Murtagh
patent: 5744306 (1998-04-01), Murtagh, Jr. et al.
Bangera et al. Genetic analysis of the 2,4-diacetylphlorglucinol Curr. Plant Sci. Biotechicol Agroc. (1994) vol. 21, pp. 383-386.
M. G. Bangera et al., "Characterization of a Locus Required for Synthesis of 2,4-Diacetylphloroglucinol by Pseudomonas aureofaciens Q2-87," Abstracts of Papers: Sixth International Congress of Plant Pathology, p. 68 (1993).
M. G. Bangera et al., "Characterization of a Locus Required for Synthesis of 2,4-Diacetylphloroglucinol by Psuedomonas aureofaciens Q2-87," Abstracts of Papers: 4th International Symposium on Pseudomonas: Biotechnology and Molecular Biology, p. 178 (1993).
M. G. Bangera et al., "Genetic Analysis of a Locus Required for Synthesis of 2,4-Diacetylphloroglucinol by Pseudomonas aureofaciens Q2-87," Phytopathology 83:1385 (1993).
D. N. Dowling and F. O'Gara, "Metabolites of Pseudomonas Involved in the Biocontrol of Plant Disease," Tibtech 12:133-141 (1994).
A. M. Fenton et al., "Exploitation of Gene(s) Involved in 2,4-Diacetylphoroglucinol Biosynthesis to Confer a New Biocontrol Capability to a Pseudomonas Strain," Applied and Environmental Microbiology 58:3873-3878 (1992).
A. M. Fenton et al., "Cloning and Heterologous Expression of Genes Involved in 2,4-Diacetylphloroglucinol Biosynthesis in Pseudomonas Strains," In Abstracts of the Fourth International Symposium on Pseudomonas: Biotechnology and Molecular Biology, Ed. R.E.W. Hancock, Vancouver, B.C., Canada, p. 49 (1993).
H. Hara et al., "Effect of Transfer and Expression of Antibiotic Biosynthesis Genes on Biological Control Ativity of Fluorescent Pseudomonads," In Improving Plant Productivity with Rhizobacteria, Eds. Ryder, Stephens and Bowen, CSIRO Division of Soils, Adelaide, South Australia, pp. 247-249 (1994).
L. A. Harrison et al., "Purification of an Antibiotic Effective Against Gaeumannomyces graminis var. Tritici Produced by a Biocontrol Agent, Pseudomonas aureofaciens," Soil Biol. Biochem. 25:215-221 (1993).
C. Keel et al., "Suppression of Root Diseases by Pseudomonas fluorescens CHAO: Importance of the Bacterial Secondary Metabolite 2,4-Diacetylphoroglucinol," Molecular Plant-Microbe Interactions 5:4-13 (1992).
C. Keel et al., "Pseudomonads as Antagonists of Plant Pthogens in the Rhizosphere: Role of the Antibiotic 2,4-Diacetylphoroglucinol in the Suppression of Black Root Rot of Tobacco," Symbiosis 9:327-341 (1990).
M. Maurhofer et al., "Influence of Enhanced Antibiotic Production in Pseudomonas fluorescens Strain CHAO on its Disease Suppressive Capacity," Phytopathology 82:190-195 (1992).
D. O'Sullivan and F. O'Gara, "Traits of Fluorescent Pseudomonas spp. Involved in Suppression of Plant Root Pathogens," Microbiol. Rev. 56:662-676 (1992).
P. Shanahan et al., "Liquid Chromatographic Assay of Microbially Derived Phloroglucinol Antibiotics for Establishing the Biosynthetic Route to Production, and the Factors Affecting Their Regulation," Analytica Chim. Acta 272:271-277 (1993).
P. Shanahan et al., "Isolation of 2,4-Diacetylphloroglucinol from a Fluorescent Pseudomonad and Investigation of Physiological Parameters Influencing its Production," Applied and Environmental Microbiology 58:353-358 (1992).
M. A. Vincent et al., "Genetic Analysis of the Antifungal Activity of a Soilborne Pseudomonas aureofaciens Strain," Applied and Environmental Microbiology 57:2928-2934 (1991).
D. Weller and L. S. Thomashow, "Microbial Metabolites with Biological Activity Against Plant Pathogens," In Pest Management: Biologically Based Technologies, Eds. R. D. Lumsden and J. L. Vaughn, pp. 173-180 (1993).
D. Weller and L. S. Thomashow, "Use of Rhizobacteria for Biocontrol," Current Opinion in Biotechnology 4:306-311 (1993).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Sequences for production of 2,4-Diacetylphloroglucinol and metho does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Sequences for production of 2,4-Diacetylphloroglucinol and metho, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Sequences for production of 2,4-Diacetylphloroglucinol and metho will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-79166

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.