Combinatorial chemistry technology: method – library – apparatus – Library – per se – Library contained in or displayed by a micro-organism or...
Reexamination Certificate
2011-04-05
2011-04-05
Steele, Amber D (Department: 1639)
Combinatorial chemistry technology: method, library, apparatus
Library, per se
Library contained in or displayed by a micro-organism or...
C435S006120, C435S040500, C435S259000, C506S009000, C506S033000, C536S023100
Reexamination Certificate
active
07919436
ABSTRACT:
The invention provides genes that are unique either toEhrlichia ruminantiumstrain Gardel or toEhrlichia ruminantiumstrain Welgevonden, or allelic couples which are present in both strains but whose sequences differ between the two strains, as genetic markers to differentiate between these two strains. The invention also provides diagnostic methods using these genetic markers.
REFERENCES:
International Search Report and Written Opinion for PCT/EP2004/013853 filed Oct. 22, 2004.
Allsopp M T et al.; “Ehrlichia ruminantiumMajor Antigenic Protein Gene (map1) Variants Are Not Geographically Constrained and Show No Evidence of Having Evolved Under Positive Selection Pressure”; Journal of Clinical Microbiology, Nov. 2001; vol. 39, No. 11; pp. 4200-4203; XP002321870.
Barbet A F et al.; “A Subset ofCowdria ruminantiumGenes Important for Immune Recognition and Protection”; Gene: An International Journal on Genes and Genomes, Elsevier Science Publishers, Barking, GB; vol. 275, No. 2; Sep. 19, 2001; pp. 287-298; XP004307852.
Demaille Jacques
Ferraz Conception
Frutos Roger
Martinez Dominique
Alston & Bird LLP
Centre de Cooperation Internationale en Recherche Agronomique po
Centre National de la Recherche Scientifique
Janssen Shannon
Steele Amber D
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