Sequence specific DNA recombination in eukaryotic cells

Details Sequence specific DNA recombination in eukaryotic cells Sequence specific DNA recombination in eukaryotic cells

2002-12-05

2009-02-17

Marvich, Maria B (Department: 1633)

Chemistry: molecular biology and microbiology

Process of mutation, cell fusion, or genetic modification

Introduction of a polynucleotide molecule into or...

C435S325000, C435S069100, C435S455000

Reexamination Certificate

active

07491539

ABSTRACT:
The present invention relates to a method of sequence-specific recombination of DNA in eukaryotic cells, comprising the introduction of a first DNA comprising a nucleotide sequence containing at least one recombination sequence into a cell, introducing a second DNA comprising a nucleotide sequence containing at least one further recombination sequence into a cell, and performing the sequence specific recombination by a bacteriophage lambda integrase Int.

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