Synthetic resins or natural rubbers -- part of the class 520 ser – Synthetic resins – From heterocyclic reactant containing as ring atoms oxygen,...
Patent
1992-11-23
1995-04-11
Kight, III, John
Synthetic resins or natural rubbers -- part of the class 520 ser
Synthetic resins
From heterocyclic reactant containing as ring atoms oxygen,...
528403, 528425, 528422, 528423, 528245, 528417, 528420, 525383, 525384, 525385, 525542, 525543, C08G 5900, C08G 6500
Patent
active
054059380
ABSTRACT:
The present invention describes a polymer composition effective to bind, in a sequence-specific manner to a target sequence of a duplex polynucleotide, at least two different-oriented Watson/Crick base-pairs at selected positions in the target sequence. The composition includes an uncharged backbone with 5- or 6-membered cyclic backbone structures and selected bases attached to the backbone structures effective to hydrogen bond specifically with different oriented base-pairs in the target sequence. Also disclosed are subunits useful for the construction of the polymer composition. The present invention further includes methods for (i) coupling a first free or polymer-terminal subunit, and (ii) isolating, from a liquid sample, a target duplex nucleic acid fragment having a selected sequence of base-pairs.
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Summerton James E.
Weller Dwight D.
Anti-Gene Development Group
Dehlinger Peter J.
Fabian Gary R.
Kight III John
Truong Duc
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