Sequence of the tropheryma whippelii bacteria rpoB gene and...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

Reexamination Certificate

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C536S023700, C536S024100, C536S024300, C536S024320, C536S024330, C435S091100, C435S091200

Reexamination Certificate

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10477915

ABSTRACT:
The invention concerns the total sequence of the Tropheryma whippelii bacteria rpoB gene, characterized in that it consists of the nucleotide sequence SEQ ID no. °9, and the nucleotide sequences derived from said sequence specific of theTropheryma whippeliibacteria and their use as probe and primer.

REFERENCES:
patent: 6074865 (2001-06-01), Kelly et al.
patent: 2791357 (1999-05-01), None
patent: WO 00/58440 (2000-10-01), None
Drancourt et al. Submitted. Mar. 8, 2000. Genbank Accession No. AF243072.
Hinrikson et al., “Detection of Three Different Types of ‘Tropheryma Whippelii’ Directly from Clinical Specimens by Sequencing, Single-strand Conformation Polymorphism (SSCP) Analysis and Type-specific PCR of their 16S-23S Ribosomal Intergenic Spacer Region,”International Journal of Systematic Bacteriology, vol. 49, pp. 1701-1706, 1999.
Raoult et al., “Cultivation of the Bacillus of Whipple's Disease,”The New England Journal of Medicine, vol. 342, No. 9, pp. 620-625, Mar. 2000.
Klenk et al., “DNA-dependent RNA polymerase subunit B as a Tool for Phylogenetic Reconstructions: Branching Topology of the Archael Domain,”Journal of Molecular Evolution, vol. 38, pp. 420-432, 1994.
Drancourt et al., “rpoB Sequence Analysis of Cultured Tropheryma Whippelii,”Journal of Clinical Microbiology, Vo. 39, No. 7, pp. 2425-2430, Jul. 2001.
Andrew Chin, “On the Preparation and Utilization of Isolated and Purified Oligonucleotides,” University of North Carolina School of Law, Mar. 9, 2002. Abridged version.

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