Septicemia suppressing substitution fluid preparation

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...

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A61K 3119

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active

054610737

ABSTRACT:
A septicemia suppressing substitution fluid preparation for controlling bacterial translocation of intestinal bacteria into blood containing at least one compound selected from the group consisting of (R)-3-hydroxybutyric acid and salts thereof is provided. In condition of septicemia, bacterial translocation of intestinal bacteria into blood is suppressed.

REFERENCES:
patent: 5292774 (1984-03-01), Hiraide et al.
Maximal Activities of Glutaminase and Some Enzymes of Glycolsis and Ketone Body Utilization and Rates of Utilization of Glutamine, Glucose and Ketone Bodies by Intestinal Mucosa After Burn Injury-M.S.M. Ardawi et al, Burns (1987) vol. 16, No. 6, pp. 438-444.
Inhibition of TPN-Associated Intestinal Mucosal Atrophy With Monoacetoacetin Scott A. Kripke, M.D. et al, Journal of Surgical Research (1988), vol. 44, No. 4, pp. 436-444.
Effect of DL-3-Hydroxybutyrate Infusions on Leucine and Glucose Kinetics in Burned Rats Receiving TPN-Alberto Maiz et al, The Journal of Nutrition, (1986) vol. 116, No.1.

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