Sepsis, adult respiratory distress syndrome, and systemic inflam

Details Sepsis, adult respiratory distress syndrome, and systemic inflam Sepsis, adult respiratory distress syndrome, and systemic inflam

1994-10-12

1998-07-14

Hutzell, Paula K.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

436 71, 436161, 436162, G01N 3353

Patent

active

057802378

ABSTRACT:
There is disclosed a diagnostic assay for adult respiratory distress syndrome (ARDS), sepsis, multiple organ dysfunction (MOD) and systemic inflammatory response syndrome (SIRS), comprising (a) measuring the amount of selected unsaturated free fatty acids (FFAs) and saturated FFAs in a body fluid, and (b) determining a ratio value comprising the sum of the unsaturated FFAs divided by the sum of the saturated FFAs. There is further disclosed a diagnostic assay for ARDS, sepsis, MOD and SIRS, comprising (a) measuring the amount of 9- or 13-hydroxyoctadecadienoic acid (HODE) and 5-hydroxy-6-trans-8,11,14-cis-eicosatetraenoic acid (5-HETE) in a body fluid, and (b) determining a ratio value of HETE and HODE.

REFERENCES:
Michailov et al., Acta Biologica et medica Germanica. 32(6):675-680, 1974.
Michailov et al., European Journal of Clinical and Biological Research, 21(10):393-397, 1974.
Akira et al, Proceedings of Congress of the Society of Psychomatic Research on Cardiosvascular Diseases, 25:10-15, 1985.
Quinlan et al., Free Rad. Res., vol. 20, No. 5, pp. 299-306, "Linoleic Acid and Protein Thiol Changes Suggestive of Oxidative Damage in the Plasma of Patients with Adult Respiratory Distress Syndrome", 1994.
Richard et al., Critical Care Medicine, vol. 18, No. 1, pp. 4-9, "Vitamin E Deficiency and Lipoperoxidation During Adult Respiratory Distress Syndrome", 1990.

Affiliated with

Also associated with

Rating

Sepsis, adult respiratory distress syndrome, and systemic inflam does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Sepsis, adult respiratory distress syndrome, and systemic inflam, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Sepsis, adult respiratory distress syndrome, and systemic inflam will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1880580