Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1981-10-01
1985-01-29
Sneed, Helen M. S.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
260403, 2604125, 260428, C09F 510, C11B 300
Patent
active
044964897
ABSTRACT:
The invention provides a process for fractionation of compounds which in essentially non-polar solvents form mixed or co-micelles and hence cannot normally be fractionated by membrane filtration. By dissolving a mixture of such compounds in a solvent system in which selective micelles formation occurs, and contacting the solution under pressure with a semipermeable membrane to separate the mixture into a permeate and a retentate, fractionation of the compound mixture can be achieved, i.e. a fraction enriched in one of said compounds can be recovered from the permeate and/or the retentate by removing solvent therefrom. The new process is in particular useful for fractionating phosphatides-containing mixtures into a fraction enriched in phosphatidyl choline by ultrafiltration of a solution of the mixture in a solvent system comprising an essentially non-polar solvent and a polar solvent, e.g. hexane-ethanol, etc., through a semipermeable membrane, and recovering a fraction enriched in phosphatidyl choline from the permeate. A fraction enriched in phosphatidyl inositol can be recovered from the retentate.
REFERENCES:
patent: 3847804 (1974-11-01), Del Pico
patent: 4093540 (1978-06-01), Gupta
patent: 4166823 (1979-09-01), Sietz
patent: 4210594 (1980-07-01), Logan et al.
patent: 4235793 (1980-11-01), Betzing
patent: 4240914 (1980-12-01), Iwama et al.
patent: 4316730 (1982-02-01), Eibl
Farrell James J.
Lever Brothers Company
Sneed Helen M. S.
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