Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters
Patent
1989-09-20
1992-05-05
Killos, Paul J.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acid esters
435146, 435259, C07L 6966
Patent
active
051109808
ABSTRACT:
Hypochlorite digestion of bacterial biomass to recover intracellular poly-.beta.-hydroxylalkanoic acid (PHA) has not been used on a large scale since it has been widely reported to severely degrade the polymer. The process of the invention proposes to optimize the initial biomass concentration, the digestion time and pH of the hypochlorite solution to minimize degradation. Consequently, PHA of up to 95% purity with an average molecular weight of 600,000 can be recovered from biomass initially containing PHA having a molecular weight of 1,200,000. By incorporating a pretreatment step with an anionic surfactant solution, PHA of 99% purity with a molecular weight of 1.20.times.10.sup.6 was obtained from biomass containing 57% PHA by weight with an initial molecular weight of 1.25.times.10.sup.6.
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Berger Eric
Braunegg Gerhart
Chavarie Claude
Ramsay Bruce A.
Ramsay Juliana
Ecole Polytechnique
Killos Paul J.
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