Separation of dissimilar amines

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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260563R, 260563C, 260563P, 2605705R, 2605708R, 2605709, 260575, 260583N, 260701, C07C 8526, C07C 8904

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active

041743512

ABSTRACT:
Amines which are dissimilar in nature by virtue of possessing different substituents, different structures or position isomers may be selectively separated by treatment with a reactive carbonyl compound and an acid. The separation may be effected at reaction conditions which include a temperature in the range of from about ambient to about 150.degree. C. and a pressure in the range of from about atmospheric to about 100 atmospheres. An example of this separation is the treatment of a mixture of m-toluidine and p-toluidine with benzaldehyde and trifluoroacetic acid. The m-toluidine will form an imine while the p-toluidine will form an acid salt.

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