Separation of diastereomers

Details Separation of diastereomers Separation of diastereomers

1986-09-16

1987-07-21

Shippen, Michael L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

560115, C07B 5700

Patent

active

046819720

ABSTRACT:
The S,S-isomers of Boc-benztine and Boc-cyclotine can be produced via the fractional crystallization of R-(+)-alpha-methylbenzylamine salt(s). The products are useful in the production of renin inhibitors.

REFERENCES:
patent: 3887615 (1975-06-01), Keith et al.
patent: 4240975 (1980-12-01), Umezawa et al.
patent: 4391986 (1983-07-01), Umezawa et al.

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